Industrial Mycology

Filamentous fungi are used by industry for manufacture of a large variety of useful products, all for the benefit of humankind. The products include metabolites, enzymes and food. Fungal cells can grow at different environmental conditions and environmental diversity. The chemical and physical conditions used for fungal propagation which depends up on fungal genetics and biology will have a great impact on the capability of these cells to accumulate the desired product(s). Fungi have high importance in the pharmaceutical and agrochemical industries due to the diverse bioactive metabolites produced by these organisms. Since the treatment of bacterial infections using partially purified penicillin century ago, bioactive fungal metabolites have strongly influenced the development of the modern pharmaceutical and agrochemical industries. Mevinolin, cyclosporine A, β-lactam antibiotics, pneumocandins, ergotamine, strobilurins, and mycophenolic acid are examples of revolutionary pharmaceuticals and agrochemicals that have a fungal origin In spite of the success of bioactive fungal metabolites as pharmaceuticals and agrochemicals, fungi remain an essentially untapped source of medicines because only a small fraction of the vast fungal kingdom has been explored for bioactive metabolite production. The potential for discovering new bioactive metabolites from fungi is unlimited. The industrial discovery of bioactive fungal metabolites is a complex, integrated, but somewhat empirical process. However, recent advances in the genetics of microbial secondary metabolite biosynthesis, genomics, and metabolic engineering will play an ever-increasing role in facilitating fungal bioactive metabolites discovery.

  • Food and Beverages Industry
  • Baking Industry
  • Mycoprotein – Quorn
  • Antibiotics – Penicillin
  • Immuno-suppressive
  • Vitamins
  • Mycodiesel
  • Fungi in waste treatment

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